Case report: Blotchy skin in a puffy neonate: is there a new association?

Introduction Purpura fulminans in the neonatal population is a rare but potentially life-threatening condition complicated by thrombosis, resultant vital organ necrosis, and gangrene of extremities. Considering rapid evolution pathogenetic mechanism, an index suspicion, early identification, prompt intervention are imperative for improved outcomes. The majority purpura cases have infectious etiology, it essential to consider other congenital acquired causes. Case description We present clinical case female neonate emphasize correlation between fulminans, chylothorax, involvement PAK2 gene, occurrence retinal detachment both eyes. After draining developed due loss protein C, S, antithrombin factors, previously not reported literature. purpuric lesions resolved after administration fresh frozen plasma. Subsequently, no recurring were noted following normalization antithrombotic factor levels serum. child also